trademark ofagingin musculus cellphone have been reversed by the overexpression of a specific protein calledNANOG . The finding by scientists from University at Buffalo record how NANOG canreverse cellular agingin muscle cells without having to reprogram the cells to a more stem cubicle - like province , which has been an approach in the past in the search to change by reversal cellular aging .
“ Our work focuses on understand the mechanisms of NANOG ’s actions in hopes of get a line druggable target in signaling or metabolic web that mimic the anti - ageing upshot of NANOG , ” says the study ’s like author Professor Stelios T. Andreadis in astatement .
Cellular ageing occurs during aging , with cells reaching a compass point where they are unable to separate and repair . This results in the genetic textile in the cells becoming unstable and causes an raiment of molecular and metabolic dysfunction that leave to disease . As a consequence , our body ’s ability to regenerate decreases over clock time – but this discipline has shown that it might not be all that forged .
By overexpressing a protein call NANOG in ageing human myoblasts ( the embryonal precursor for muscle cells ) in the science lab , scientist could overturn the age - related deterioration of the cell and increase their deoxyribonucleic acid repair mechanisms . Furthermore , in experiments involving creature , they show that NANOG overexpressed in prematurely - aging mice increased the figure of musculus stem electric cell represent , show that NANOG might have rejuvenating dimension that could help reverse the aging process .
" finally , the study could help take to new treatments or therapy that aid reverse cellular agedness , and aid the many people suffering from age - related disorders , ” adds Stelios T. Andreadis .
In the pursuit to stanch and reverse the get on cognitive process , various tread have been made in the last . Just last month , a studyshowed that a supplement could reverse the hallmarks of old age and promote respectable ripening .
The latest discovery was published in the journalScience .
