Despite having completely altered the history of London during the end of the 17th hundred , factual grounds of the bacteria responsible for for the Great Plague has remained elusive . But after hear a mass grave of plague victims in 2011 while retrace a newfangled underground railway system in primal London , archaeologists have make out to identifythe DNA from theYersinia pestisbacterium that get the disease .

“ This is a tremendously pregnant discovery as it is the first designation of ancient DNA from the 1665 Great Plague in Britain,”explainsDon Walker , senior osteologer at theMuseum of London Archaeology , who has spend the last five years analyzing all the remains unearthed . “ This uncovering has the potential to greatly heighten scientists ' reason of the disease and coupled with elaborated inquiry of the skeleton reveal more about this devastating epidemic and the lives of its victim . ”

It has been during the construction of Crossrail – the largest construction project in Europe – as it tunnel its way under London , that theengineers discoveredover 3,500 remains in what was once Bedlam burial ground . The stupefying find of the plague pit has pay researchers an unparalleled glimpse into what was going on during one of the most notorious periods of the city ’s history , as well as providing an incredible record of the people who were living in London in the 1660s .

It was during this point that what is now roll in the hay as the Great Plague swept through London , kill an estimated100,000 people , think to account for up a quarter of the entire city at the prison term . The epidemic that collide with in 1665 was actually of a modest scale than the earlier Black Death , but has been etched into the metropolis ’s cognisance by Daniel Defoe ’s resonant Ketubim of the event in the other 18th century .

More than   five years since the breakthrough of the mass graveat Liverpool Street , which is to become a fresh ticket hall for the railway , archaeologists have been studying those who succumbed to the disease , and have finally been able-bodied to isolate theY. pestisbacterium .

Interestingly , the passel grave at Liverpool Street is   also able to reveal another face of the pest as it swept through London . Despite Defoe writing at the time , “ Tis sure they died by spate and were entomb by scores ; that is to say , without report , ” the burial were really very ordered , with the team of archaeologists settle from the positioning of the skeletons that they had all been laid to rest in casket . It seems that even when scads were dying due to the pest , the bushed were still treated with regard , though it is also possible that by the end of the epidemic disorder began to spread out .